Green synthesis of new hippuric hydrazones
Publish place: Asian Journal of Green Chmistry، Vol: 4، Issue: 2
Publish Year: 1399
Type: Journal paper
Language: English
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Document National Code:
JR_AJGC-4-2_002
Index date: 22 July 2020
Green synthesis of new hippuric hydrazones abstract
Hippuric hydrazones 4–8 were prepared starting from treating the corresponding acid with ethanolic HCl forming the corresponding ester 2. The formed ester was then converted to ethyl hippurate 3 by treating the ester with hydrazine hydrate. The formed ethyl hippurate was then irradiated with various substituted aromatic aldehydes under solvent-free conditions forming new series of hippuric hydrazones 4–8. Developing clean synthetic route for synthesizing hippuric hydrazones is the main point of this work which is environmentally and economically desirable. The synthesized compounds were confirmed by spectral NMR, mass, IR and CHN analysis data.
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Green synthesis of new hippuric hydrazones authors
Harith M. Al-Ajely
Department of Chemistry, College of Science, University of Mosul, Mosul, Iraq
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