The Effects of Eight Weeks Aerobic Interval Exercise with Variable Volume on the Cardiovascular Risk Factors and Liver Enzymes of Women with Dyslipidemia

Introduction: Metabolic dyslipidemia could lead to non-alcoholic fatty liver disease, and its secondary consequence is the development of metabolic syndrome and diabetes. The present study aimed to investigate the effects of eight weeks of aerobic interval exercise with variable volumes on the cardiovascular risk factors and liver enzymes of the women with dyslipidemia. Methods: This quasi-experimental study was conducted on 30 middle-aged women with high blood lipids. The patients were selected and divided into three groups of low-volume training (three sessions per week; n=10; LVT), high-volume training (four sessions per week; n=10; HVT), and control (n=10; C).The exercise program was implemented in eight weeks 3-4 sessions per week for 45-60 minutes with the intensity of 65-75% of the maximal heart rate. The inter-group and intra-group comparison were performed using student s t-test, and one-way analysis of variance (ANOVA) was used to assess the differences between the groups. Results: In the training groups, a significant reduction was observed in weight (LVT: 72.01 vs. 67.26, HVT: 72.80 vs. 68.06), body mass index (LVT: 28.19 vs. 26.31, HVT:27.85 vs. 26.04), body fat (LVT: 26.86 vs. 25.69, HVT:27.21 vs. 25.91), waist-to-hip ratio (LVT: 1.05 vs. 1.03, HVT:1.07 vs. 1.05), alanine transaminase(LVT: 46.60 vs. 39.60, HVT: 43.80 vs. 38.50), aspartate transaminase(LVT: 36.50 vs. 31.00, HVT: 33.50 vs. 29.40), and triglyceride (LVT: 171.80 vs. 163.60, HVT:176.90 vs. 161.40). However, the maximum oxygen uptake increased significantly after the intervention in both the training groups (LVT: 32.17 vs. 35.93, HVT:30.93 vs. 35.98). The levels of total cholesterol (211.20 vs. 204.90) and low-density lipoprotein cholesterol (134.13 vs. 126.68) significantly decreased only in the LVT group, while no such changes were observed in the HVT group. In addition, the systolic blood pressure (LVT: 135.40 vs. 128.60, HVT: 137.00 vs. 129.60) decreased significantly in both groups, while no significant change was observed in the diastolic blood pressure. Conclusion: According to the results, eight weeks of aerobic interval exercise could improve the cardiovascular risk factors, liver enzymes, and body composition of the women with dyslipidemia. Therefore, it is recommended that some cardiovascular risk factors and liver enzymes of women with dyslipidemia be used for the improvement of these patients.

Keywords:

Dyslipidemia , Liver enzymes , lipid profile