The Effect of Aerobic Training with Purslane (Portulaca Oleracea) Seed on Toll Like Receptors in Colon Tumor Tissue of Adult Rats with Colon Cancer
Publish place: Jorjani Biomedicine Journal، Vol: 7، Issue: 4
Publish Year: 1398
نوع سند: مقاله ژورنالی
زبان: English
View: 292
This Paper With 8 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
این Paper در بخشهای موضوعی زیر دسته بندی شده است:
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_JOBJ-7-4_007
تاریخ نمایه سازی: 27 بهمن 1399
Abstract:
Background and objective: Exercise and nutrition are two factors influencing the improvement of inflammatory markers in patients with colon cancer. Aim of present study was to investigate the effect of aerobic training (AT) with Purslane (Portulaca Oleracea) Seed (PS) on toll like receptor 2 (TLR-2) and TLR-4 in colon tumor tissue of rats with colon cancer.
Methods: In this experimental study 30 adults rats were divided into five groups of six rats including: 1) healthy control, 2) control, 3) training, 4) PS, and 5) training + PS. Colon cancer induced by intra-peritoneal injection of azoxymethane in groups 2- 5. During eight weeks, groups 3 and 5 performed AT for five sessions per week also groups 4 and 5 received 75 mg/kg PS intra-peritoneally. TLR2 and TLR4 protein levels were measured by ELISA method. For review the normal distribution and data Shapiro- wilk was used and for statistical analysis of data one way ANOVA with Tukey’s post- hoc tests were used (P≤0.05).
Results: Training had not significant effect on TLR-2 (P=0.91) and TLR-4 (P=0.95); PS and training + PS significantly decreased TLR-2 and TLR-4 (P=0.001) also training + PS had more favorable effect on decrease of TLR-2 compare to training and PS alone (P=0.001).
Conclusion: Although PS alone can improve TLR-2 and TLR-4 levels in colon tumor tissue of adult rats with colon cancer, nevertheless it appears that AT along with PS have more favorable effects on improvement of TLR-2 compare to training and PS alone.
Keywords:
Authors
Abdol Kheder Keshtvarz
Department of Sport Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran
Maghsoud Peeri
Department of Sport Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran
Mohammad Ali Azarbayjani
Department of Sport Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran
Seyed Ali Hosseini
Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :