Paget disease of the vulva: report 5 cases and literature review
Publish Year: 1399
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JOGCR-6-1_008
تاریخ نمایه سازی: 28 بهمن 1399
Abstract:
Vulvar Paget’s disease is rare among patients with vulvar cancer. Commonly, this disease is presented in the vulva and seen in postmenopausal women. In this study, we reported five cases of vulvar Paget’s disease referred to Bahman Hospital, Tehran, Iran, from 2013 to 2019.
The median age of patients diagnosed with Paget’s vulvar disease was 56.2 years (ranges from 52 to 62 years); the oncology history of patients was negative. All patients underwent surgery, including wide local excision, hemivulvectomy, and bilateral vulvectomy. The invasive disease was observed in three patients. Surgical margins in three patients were involved by Paget’s disease, and one recurrence (25%) was observed. Paget’s disease should be diagnosed and treated by surgery as soon as possible to avoid worsening the prognosis of patients and recurrence.
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Authors
Nadereh Behtash
Department of Gynecologic oncology, Tehran university of medical sciences cancer center, Tehran , Iran
Fahimeh Sabet
Department of Gynecologic oncology, Isfahan university of medical sciences cancer center, Isfahan , Iran
Narges Izadi-mood
Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran
Mojgan Karimi-Zarchi
Iran University of Medical Sciences (IUMS), Tehran, Iran
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