The Effect of Combining Essences of Myrtus Communis and Melissa Officinalis in the Treatment of Minor Aphta

Background and Objective: Minor aphta has a high incidence in the populations ranging from ۲-۵۰%. In spite of its frequency and severity of discomfort, there is not an absolute treatment for it. So, the main objective of this study was to evaluate the efficacy of a herbal medicine in the control of Minor aphta.    Materials and Methods: In this double-blind, randomized study ۱۳۷ patients with Minor aphta (with not more than four days from the onset) were selected and then placed into one of the groups of A (solution containing ۵ percent Myrtus communis and Melissa officinalis in ethanol ۸۰) and B (solution containing ۱۰ percent Myrtus communis and Melissa officinalis in ethanol ۸۰) or C (placebo containing ethanol ۸۰). Results: Mean duration for complete recovery in minor aphta was ۳/۵ days in group A, ۷/۵ days in group B and ۷/۳ days in group C. These results showed a significant statistical differences in the three groups (p<۰/۰۰۰۵). Conclusion: The results of this study revealed that using a combination of Myrtus Communis and Melissa Officinalis plants was effective in the treatment of RAS. In order to obtain the accurate concentrations of the ingredients of this compound, further studies are necessary.

Keywords:

Myrtus communis , Melissa officinalis , RAS (Recurrent Aphtous Stomatits) , Mouth diseases