The Effect of Vaginal Probiotic Capsule On Vaginal Colonization and Treatment Results in Patients with Vulvar and Vaginal Candidiasis
Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
View: 263
This Paper With 11 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_ZUMS-26-114_004
تاریخ نمایه سازی: 11 اردیبهشت 1400
Abstract:
Background and Objective: Generally, ۷۵% of women experience vaginal candidiasis at least once in their lifetime. This study aimed to determine the effect of lactobacillus rhamnosus vaginal probiotic capsule on vaginal colonization and treatment results after treating vulvar and vaginal candidiasis.
Materials and Methods: This double-blind clinical trial was conducted in ۵۸ women suffering from vulvar and vaginal candidiasis (based on swab cultures). After treating the patients with clotrimazole ۲% vaginal cream, the samples were randomly assigned to probiotic (n=۲۸) and placebo (n=۳۰) groups. While first group took lactobacillus rhamnosus vaginal probiotic capsules twice a day for one week, the second group used vaginal placebo capsules. The patients were examined regarding swab cultures, vaginal lactobacillus colonization, vaginal pH, and clinical symptoms of vulvar and vaginal candidiasis ۲-۵ days before and ۱ month after taking the capsules. Then, the data were fed to SPSS and analyzed using Chi-square, Fisher’s exact test, repeated measures ANOVA, and post-hoc test.
Results: The results showed no significant difference between the two groups concerning the results of fungal culture. Moreover, despite the increase in vaginal lactobacillus colonization in the probiotic group, no significant difference was found between the two groups at different time periods (p=۰.۲۵۵). The results also showed no significant difference between the two groups regarding the mean change of vaginal pH at different time periods (p=۰.۴۸۰).
Conclusion: It seems that using vaginal lactobacillus rhamnosus probiotic capsules was somewhat effective in vaginal lactobacilli colonization in patients with vaginal candidiasis. However, it was not effective in pH changes and treatment results.
Keywords:
Authors
سارا عظیما
Dept Midwifery, Faculty of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
سمیه هوشیار
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
محمد معتمدی فر
AIDS Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
معصومه کاویانی
Dept Midwifery, Faculty of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
نجف زارع
Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :