The Effect of Anethum Graveolens L. (Dill) on Lipid Profile in Adults with Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Controlled Clinical Trials
Publish place: Critical Comments in Biomedicine، Vol: 2، Issue: 1
Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_CCB-2-1_006
تاریخ نمایه سازی: 29 اردیبهشت 1400
Abstract:
ABSTRACT Background: Several randomized clinical trials (RCTs) has assessed the effect of Anethum graveolens L. (AG) or dill supplementation on lipid profile in adults with cardiovascular risk factors with different results. Therefore, we decided to conduct a systematic review and meta-analysis regarding the available randomized controlled trials to assess AG supplementation's efficacy on lipid profile in adults with cardiovascular risk factors. Methods: PubMed, Embase, Cochrane's database, Ovid, Web of Science, ProQuest, Scopus, and Google Scholar were searched to find relevant articles investigating the effect of AG on the lipid profile of adults with risk factors for cardiovascular disease up to December ۲۰۲۰. Six trials with seven treatment armsmet the inclusion criteria. A random-effects model was used in the meta-analysis. To test heterogeneity, I۲ statistics and Cochrane Q test were applied. Results: The results reported a significant improving effect of AG on TG [WMD = -۲۹.۲۰, ۹۵% confidence interval (CI): -۳۴.۷۳,-۲۳.۶۸ mg/dL, p < ۰.۰۰۱], TC (WMD = -۱۶.۴۶, ۹۵%CI: -۲۱.۵۴,-۱۱.۳۹ mg/dL, p < ۰.۰۰۱), LDL-C (WMD = -۱۳.۹۰, ۹۵%CI: -۱۶.۰۸, -۱۱.۷۲ mg/dL, p < ۰.۰۰۱), and HDL-C (WMD = ۴.۰۱, ۹۵%CI: ۳.۴۸, ۴.۵۴ mg/dL, p < ۰.۰۰۱). Conclusion: This meta-analysis of randomized controlled clinical trials revealed that consuming AG extract for more than six weeks might improve lipid profile in adults with cardiovascular risk factors.
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Authors
Anahita Mansoori
Department of Nutrition, School of Para-Medical Sciences, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
Zahra Salimi
Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Seyed Ahmad Hosseini
Department of Nutrition, School of Para-Medical Sciences, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
Razie Hormoznejad
Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran,
Maryam Asadi
Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
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