MicroRNA ۲۱۰ as a Biomarker in Breast Cancer

The increasing literature exploring the role of circulating miR-۲۱۰ has clarified its potential as a promising biomarker for early detection, diagnosis and prognosis. Measuring circulating miR-۲۱۰ levels could be a non-invasive method for early cancer detection. Even if, to date, most studies appear to be preliminary it seems that miR-۲۱۰ will be a good target for drug development. In this study, we had detected the difference of serum miR-۲۱۰ expression between health and breast cancer patients. total of ۱۵ breast cancer patients were selected for the breast cancer (BC) group and ۱۵ healthy people. The results showed The expression level of miR-۲۱۰ in the serum of breast cancer patients was significantly higher compared with that in healthy individuals. Patients with breast cancer present increased levels of circulating miR-۲۱۰; thus, circulating miR-۲۱۰ may be a potential biomarker of tumor presence and therapeutic response in breast cancer

Keywords:

Cancer , biomarker , miR-۲۱۰ , Gene expression