Antimicrobial activity of methanol extract of Citrullus colocynthis against antibiotic-resistant Staphylococcus aureus
Publish place: Future Natural Products، Vol: 4، Issue: 3
Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JHPH-4-3_003
تاریخ نمایه سازی: 11 خرداد 1400
Abstract:
Background and aims: Staphylococcus aureus and anaerobic gram-positive cocci, are medically the most important species in the genus Staphylococcus. Sometimes, the bacteria are called S. aureus. The constantly growing antibiotic-resistant bacterium is very important in treatments. The aim of this study is to evaluate the antimicrobial activity of ethanol extract from Citrullus colocynthis against the S. aureus resistant to antibiotics.Methods: S. aureus strains were isolated from the city of Zabol and C.colocynthis extract was prepared using rotary devices and the MIC and MBC were determined by microdilution method. Results: The results of this study showed that the extract from C. colocynthis inhibits the growth of bacteria in different concentrations, and that despite the relative strength of most species with different concentrations, the highest sensitivity was observed in concentrations of ۱۰ and ۲۰ mg/ml, in which is ۱۰۰% bacteria were gone. C. colocynthis extract at a concentration of approximately ۵ mg /ml had the highest inhibitory effect. Conclusion: The results showed high antimicrobial effects of ethanol extract of C. colocynthis, which can offer appropriate drug therapy.
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Authors
Khadije Rezaie Keikhaie
Department of obstetrics and gynecology, maternal and fetal health research center, Zabol University of Medical Sciences, Zabol, Iran
Saeedeh Ghorbani
۲. Department of Biology, Faculty of Science, Payam Nor ,University of Tehran, Tehran, Iran
Zahra Hosseinzadeh
۳. Department of Biology, Faculty of Sciences, University of Guilan, Rasht, Iran
Mehdi Hassanshahian
Department of Biology- Faculty of Scienc- Shahid Bahonar University of Kerman- Kerman- Iran.
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