Genetics and epidemiology of Middle East Respiratory Syndrome-Coronavirus (MERS-CoV)
Publish place: Epidemiology and Health System Journal، Vol: 2، Issue: 4
Publish Year: 1394
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_INJER-2-4_008
تاریخ نمایه سازی: 22 خرداد 1400
Abstract:
Background and aims: Middle East respiratory syndrome (MERS) is a viral respiratory illness caused by a coronavirus. After the primary onset of MERS in Saudi Arabia, in September ۲۰۱۵ cases began to increase. The number of laboratory-affirmed cases by MERS-CoV in the Middle East has been being increased recently. Methods: In this current review article, by using the terms “MERS” and “coronavirus” we first searched for English language articles in the PubMed database, published in last five years. Then by a detailed review of related articles, we provided a comprehensive information about epidemiology, genetic, host and coronavirus treatment. Results: More importantly, evidences of human-to-human transmission in Europe and America indicate that the viral adaptations in humans may precede a large-scale epidemic. The genome of Coronaviruses is a linear positive-sense single stranded large RNA and they are enveloped viruses that have a helical symmetric nucleocapsid. Some new insights have been provided in previous few months in to the animal Coronavirus hosts, transmissibility, contagion of MERS Co-V and ideal laboratory diagnostic methods. Conclusion: It seems crucial to control this new human infection “MERS-CoV” by collaborating global and local health authorities and their continual support for further research on it.
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Authors
Fereshteh Ahmadinejad
Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
Mohammad-Amin Honardoost
Division of cellular molecular biology, Department of Biology, Faculty of Science. University of Isfahan
Masoud Amiri
Social Health Determinants Research Center, Shahrekord University of Medical sciences, Shahrekord, Iran
Mohammad-Saeid Jami
Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
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