Primary Leiomyosarcoma of the Breast: A Rare Case Report

Background: Primary leiomyosarcoma (LMS) of the breast is a very rareneoplasm of the breast arising from the mesenchymal tissue. The clinicalpresentation of this entity simulates other benign and malignant lesions ofmesenchymal tissue of the breast.Case presentation: Case 1:A40-year-old female presented with a right-sidedbreast lump, which was suspected to be a malignant spindle cell tumor on needlecore biopsy (NCB). A multi-disciplinary team performed modified radicalmastectomy (MRM) with axillary node dissection on the patient with no postoperativechemo-radiation. Case 2: A 70-year-old female presented with a leftsided breast lump and a palpable axillary node. Needle core biopsy diagnosed it asmalignant spindle cell tumor. The patient underwent MRM with axillary nodedissection. It was confirmed to be a case of breast LMS with axillary nodalmetastasis. Both patients were followed up for one year with no evidence ofrecurrence.Conclusion: Both cases underwent MRM with axillary node dissection in ourstudy. However, the role of axillary dissection in the prognosis and disease-freesurvival of the patientswith primary LMS of the breastwith axillarymetastasis hasnot been studied yet. The optimal management of this entity remains to be tumorexcision with clear margins.

Primary Leiomyosarcoma of the Breast: A Rare Case Report Keywords:

Leiomyosarcoma , axillary metastasis , modified radical mastectomy