Targeting Breast Cancer With Bio-inspired Virus Nanoparticles
Publish place: Archives of Breast Cancer، Vol: 5، Issue: 2
Publish Year: 1397
Type: Journal paper
Language: English
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JR_ARCHB-5-2_004
Index date: 14 June 2021
Targeting Breast Cancer With Bio-inspired Virus Nanoparticles abstract
Background: Viral nanoparticles are biodegradable, biocompatible, selfassembling,and highly symmetric, and can be produced in large quantities.Several plant viral nanoparticles (VNPs) have been exploited in different areas ofnanobiotechnology, especially drug delivery in cancer therapy. In this study, aflexuous plant virus called potato virus X (PVX) is presented with a uniquenanoarchitecture which can increase tumor homing and penetration. Thus, thisstudy aimed to investigate the potential of PVX for delivering Herceptin (HER) indifferent breast cancer cells and normal cells.
Targeting Breast Cancer With Bio-inspired Virus Nanoparticles Keywords:
Breast cancer cell lines , cytotoxicity , Herceptin , plant viral nano particles , Potatovirus X (PVX)
Targeting Breast Cancer With Bio-inspired Virus Nanoparticles authors
Neda Esfandiari
Department of Nanobiotechnology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran