Resolved of Respiratory Failure Following the Use Pulse-Doses of Methylprednisolone in a Cytokine Storm Related to ۲۰۱۹ novel coronavirus

Since mid-December of ۲۰۱۹, an outbreak of pneumonia has been spread from Wuhan City, Hubei province, China, as a viralpneumonia. After virus identification and isolation, the pathogen for this pneumonia was originally called ۲۰۱۹ novelcoronavirus (۲۰۱۹-nCoV). ۲۰۱۹-nCoV has been associated with progressive cytokine storm leading to a hyper-inflammatorystate that this state associated with respiratory failure. We hereby reported a known case of Rheumatoid arthritis, Hypertensionand Coronary artery bypass graft that confirmed ۲۰۱۹-nCoV and he was associated with progressive cytokine storm leading torespiratory failure. After corticosteroid administration, respiratory failure and extremely high levels of IL۶ respondeddramatically to pulse-doses of Methylprednisolone. We concluded that pulse-doses of Corticosteroids can be effective incontrolling and relieving cytokine storms and related respiratory failure.

Keywords:

Cytokine Storm , Interleukin-۶ , ۲۰۱۹ novel coronavirus , Respiratory Failure , Systemic Corticosteroid