Antihypertensive Medications in Hypertension Control in Male Industrial Employees: a Retrospective Cohort Study

Aims: Hypertension control is one of the most important healthcare issues in all societies. One way to control high blood pressure is to use antihypertensive medications. Therefore, this research was to study the effect of antihypertensive drugs on changing blood pressure, Body Mass Index, and Framingham Risk Score. Instrument & Methods: This retrospective cohort study (from January ۲۰۱۴ to January ۲۰۱۸) was done on male workers who work in Mobarakeh steel company using the census method by referring to the workerschr('۳۹') medical records. The case group (n=۶۴۲) was hypertensive people who took medications for controlling hypertension, and the control group (n=۱۵۵۵) was healthy people without using any hypertension drug. The FRS is a gender-specific algorithm used to estimate the ۱۰-year risk of cardiovascular in individuals. The blood pressure of both arms was measured by three general practitioners using a calibrated portable or wall-mounted Baumometer sphygmomanometer Kompak Model-۲۶۰mmHg. Data were analyzed by independent t-test and multilevel modeling using R ۳.۲.۱ software. Findings: ۲۱۹۷ male workers participate. This study showed that changes in SBP, DBP, and FRchr('۳۹')s variables during ۲۰۱۴ to ۲۰۱۹ in the case group compared to the control group had a significant decrease (p<۰.۰۰۱). Nevertheless, this decrease was not significant for the BMI (p=۰.۵۸۸). Conclusion: The use of antihypertensive drugs is a very effective method in controlling hypertension patients. Therefore, the priority of pharmacological method in the treatment of this patient is much more effective than other methods.

Keywords:

Antihypertensive medications , Hypertension , Blood Pressure