The Clinical Outcome of Patients Undergoing Fontan Surgery; Over ۱۰ Years of Experience in a Single Center

Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_INJPM-9-8_012

تاریخ نمایه سازی: 10 شهریور 1400

Abstract:

Background: The modified Fontan operation is one of the essential surgical techniques in children with congenital heart diseases. Thus, we sought to identify the characteristics as well as the early and late outcomes of patients who have undergone Fontan operation during more than ۱۰ years. Methods: The medical records of ۵۲ patients who underwent modified Fontan operation from March ۲۱th, ۲۰۰۶ to March ۲۰th, ۲۰۱۸, at Tabriz Children's Hospital including the baseline, clinical and surgical data were extracted and reviewed. Patients were invited for follow up visits and clinical examination and echocardiographic evaluations were conducted. Findings: The most prevalent heart anomaly was tricuspid valve disorders (۲۸ cases, ۵۱.۹%). The majority of patients (۴۲ cases, ۸۰.۲ %) underwent intracardiac lateral tunnel Fontan. The most prevalent complications were prolonged pleural effusion and neurologic events (each one in ۱۰ cases, ۱۹.۲%). The in-hospital mortality rate was ۱۵.۳%. The patients were followed for a median of ۷ years. The survival of those successfully followed was ۷۵ percent. The most common valvular disorder was mitral valve regurgitation (MR), which was present in ۸۴% of cases. The group of patients with single ventricle had a significantly higher mortality rate than the other groups (P = ۰.۰۱۸). Conclusion: Survival rate of patients undergoing a Fontan completion is acceptable. However, patients remain at risk for morbid events. Moreover, patients with Fontan circulation should be strictly followed to investigate the development of MR and to timely repair in severe cases to prevent further deterioration. Of note, due to some limitations of our study, further multi-centric studies are required to confirm our findings.

Keywords:

complication , extracardiac Fontan , Fontan operation , intracardiac lateral tunnel Fontan , Outcome

Authors

Shamsi Ghaffari

Pediatric Health Research Center, Tabriz Children Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

Ahmad Jamei Khosroshahi

Pediatric Health Research Center, Tabriz Children Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

Mahmoud Samadi

Pediatric Health Research Center, Tabriz Children Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

Akbar Molaie

Pediatric Health Research Center, Tabriz Children Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

Mohammadreza Baghaei

Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Tahereh Basir

Pediatric Health Research Center, Tabriz Children Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

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