Interaction of Epirubicin (Ep) and Novel CMC-CdTe / ZnS QDs nanosensor

Cancer named as a group of disease that causes abnormal cell growth with the ability to spread to other parts of body. Epirubicin (Ep) is one of medicine that commonly used for cancer treatment. Evaluation of low concentrations of this drug in body samples requires sensitive, rapid, and accurate analysis methods. Here we report the interaction of novel CMC-CdTe/ZnS QDs nanosensor with Ep. In the presence of ۳۶.۴۵ × ۱۰−۶ mol/L Ep ۹.۵% of fluorescence intensity of CMC-CdTe/ZnS QDs was quenched at ۵۷۵ nm. This obviously illustrated that CMC -CdTe/ZnS QDs could good interact with Ep and decrease fluorescence intensity of these nanosensor.

Keywords:

Nanosensores , Quantum dots , carboxymethyl cellulose , Drug determination