Antileishmanial and antibacterial activities of biologically synthesized silver nanoparticles using Alcea rosea extract (AR-AgNPs)
Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JWENT-6-3_007
تاریخ نمایه سازی: 11 مهر 1400
Abstract:
Recent developments in nanotechnology lead to draw scientist's interest in green synthesis nanoparticles because of their importance in all fields of sciences. This paper is an overview of Ag nanoparticles biosynthesis (AgNPs) by aerial part of Alcea rosea extract. Synthesis procedures were described, with no stabilizers or surfactants. The synthesized AR@AgNPs were characterized using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction analysis (XRD), and UV-Vis analysis. The UV-Vis spectrum of AR@AgNPs shown a characteristic surface plasmon resonance (SPR) peak at ۴۲۵ nm. Scanning electron microscope revealed spherical shaped with a diameter range of ۱۰-۳۰ nm. Energy dispersive X-ray spectroscopy analysis demonstrated the peak in silver region confirming presence of elemental silver. Evaluation of the antibacterial and antileishmanial activity of biosynthesized silver nanoparticles was performed. AR@AgNPs exhibit effective antibacterial activity against seven ATCC strains of bacteria and eight strains of drug-resistant bacteria. Also, their activity against leishmaniasis was studied on both promastigotes and amastigotes.
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Authors
Zahra Hashemi
Department of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran
Mina Shirzadi-Ahoodashti
Department of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran
mohammad ali Ebrahimzadeh
Department of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran.
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