Prevalence of Acute Kidney Injury in Patients with Sepsis in Isfahan, Iran

Introduction: Acute kidney injury (AKI) is one of the most prevalent and extreme physio-pathological disorders in hospitalized patients, ۲۰-۴۰% of whom are hospitalized in the intensive Care Unit (ICU). Sepsis is the most commonplace reason for AKI in intensive care patients, accounting for ۵۰% of ICU casesMethods: This was a descriptive cross-sectional study conducted at Isfahan University of Medical Sciences from ۲۲ October ۲۰۱۶ to ۲۲ October ۲۰۱۷. Two hundred and thirty-two selected patients at Al-Zahra Hospital in Esfahan were enrolled in the study. Patients were followed for ۱۰ days to determine the short-term mortality rate. Data were analyzed using t-test and Chi-squared test using SPSS software (ver. ۱۶).Results: In this study, ۲۳۲ patients with sepsis were evaluated. Their mean age (± standard deviation) was ۶۹.۹ (۱۸.۴) years. The mean age of patients with acute kidney Injury (۷۲.۷ years) was significantly higher than the mean age of non-patients (non-AkI) (۶۶.۶ years) (p-value= ۰.۰۱۲). However, the significant difference was not between the age groups, but the p-value was near the significant border. The mortality rate of patients (۵۳.۶%) was significantly higher than the non-patients (non-AKI) (۲۹.۶%) (p-value<۰.۰۰۰۱).Conclusions: This study showed that the prevalence of AKI was ۵۷.۳%, which was similar to the prevalence rate in other countries. A relationship was also demonstrated between AKI and mortality rate and showed that AKI increases the mortality rate.

Keywords:

demographics , Sepsis , Acute kidney injury