Understanding the Effect of Natural Products on Breast Cancer via P۵۳-MDM ۲ Signal Pathway

Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
View: 192

This Paper With 9 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

این Paper در بخشهای موضوعی زیر دسته بندی شده است:

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_JCMR-13-1_009

تاریخ نمایه سازی: 22 آذر 1400

Abstract:

The use of medicinal plants in the treatment of diseases has a long history dating back to the presence of humans on earth. Cancer has almost been an incurable disease, and among the various cancers, breast cancer is the most common type of cancer among women and imposes an enormous burden on patients. Although medical and surgical solutions have been proposed for the disease, it has not been successful enough to treat the disease in many patients. In recent years, more studies have been done on the effects of medicinal plants on breast cancer, and scientists are trying to find the exact mechanisms of action for these plants to find effective ways for controlling cancer cell growth.  This article focuses on P۵۳ and MDM۲, two very important genes involved in regulation of cell growth and proliferation both in cancer and normal tissue, and we also gathered the list of natural compounds targeting the MDM۲-p۵۳ pathway. Our results provide a list of plant families that can influence this pathway and have great potential in designing treatments against cancers that encompass deregulation of the MDM۲-p۵۳ pathway.

Authors

Zahra Ghavidel

Department of Biology, Faculty of Sciences, Hakim Sabzevari University, Iran

Madjid Momeni Moghaddam

Department of Biology, Faculty of Sciences, Hakim Sabzevari University, Iran

Toktam Hajjar

Department of Biology, Faculty of Sciences, Hakim Sabzevari University, Iran

Eisa Kohan-Baghkheirati

Department of Biology, Faculty of Sciences, Hakim Sabzevari University, Iran

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
  • Baraya. Y. S., K. K. Wong and N. S. Yaacob ...
  • Bellazzo. A., D. Sicari, E. Valentino, G. Del Sal and ...
  • Brekman. A., K. E. Singh, A. Polotskaia, N. Kundu and ...
  • Brown. C. J., S. Lain, C. S. Verma, A. R. ...
  • Cabral. B. L. S., A. C. G. da Silva, R. ...
  • Chandler. D. S., R. K. Singh, L. C. Caldwell, J. ...
  • Choobkar. N., S. Kakoolaki and F. Mohammadi (۲۰۱۷). The biological ...
  • Cicalese. A., G. Bonizzi, C. E. Pasi, M. Faretta, S. ...
  • Cordon-Cardo. C., E. Latres, M. Drobnjak, M. R. Oliva, D. ...
  • de Oca Luna. R. M., D. S. Wagner and G. ...
  • Evans. S. C., M. Viswanathan, J. D. Grier, M. Narayana, ...
  • Gopal. Y. V., E. Chanchorn and M. W. Van Dyke ...
  • Gupta. A., K. Shah, M. J. Oza and T. Behl ...
  • Hsu. Y.-L., Y.-H. Uen, Y. Chen, H.-L. Liang and P.-L. ...
  • Key. T. J., P. K. Verkasalo and E. Banks (۲۰۰۱). ...
  • Khan. F., F. Ahmed, P. N. Pushparaj, A. Abuzenadah, T. ...
  • Khazaei. M., M. Yadegari and R. Ghorbani (۲۰۰۶). SURVEY OF ...
  • Kim. S., J. Han, N.-Y. Kim, S. K. Lee, D. ...
  • Klei. C. and L. Vassilev (۲۰۰۴). Targeting the p۵۳–MDM۲ interaction ...
  • Kubatka. P., M. Kello, K. Kajo, M. Samec, K. Jasek, ...
  • Kubatka. P., M. Kello, K. Kajo, M. Samec, A. Liskova, ...
  • Kubatka. P., S. Uramova, M. Kello, K. Kajo, M. Samec, ...
  • Lane. D. P. (۱۹۹۲). p۵۳, guardian of the genome. Nature ...
  • Lang. S. J., M. Schmiech, S. Hafner, C. Paetz, K. ...
  • Lee. E., H. To, J.-Y. Shew, R. Bookstein, P. Scully ...
  • Lee. E. Y. and W. J. Muller (۲۰۱۰). Oncogenes and ...
  • Li. H., Q. Liu, Z. Wang, R. Fang, Y. Shen, ...
  • Li. M., Z. Zhang, D. L. Hill, X. Chen, H. ...
  • Liu. L., J. Yan, Y. Cao, Y. Yan, X. Shen, ...
  • McCann. A., A. Kirley, D. Carney, N. Corbally, H. Magee, ...
  • McGrowder. D. A., F. G. Miller, C. R. Nwokocha, M. ...
  • Mitra. S. and R. Dash (۲۰۱۸). Natural Products for the ...
  • Nagamine. M. K., T. C. da Silva, P. Matsuzaki, K. ...
  • Najmuddin. S. U. F. S., M. F. Romli, M. Hamid, ...
  • Park. E. Y., Y. Woo, S. J. Kim, D. H. ...
  • Parker. S. L., T. Tong, S. Bolden and P. A. ...
  • Portman. N., H. H. Milioli, S. Alexandrou, R. Coulson, A. ...
  • Proietti. S., A. Cucina, G. Dobrowolny, F. D'Anselmi, S. Dinicola, ...
  • Qin. J.-J., S. Sarkar, S. Voruganti, R. Agarwal, W. Wang ...
  • Qin. J.-J., W. Wang, S. Sarkar, S. Voruganti, R. Agarwal ...
  • Qin. J.-J., W. Wang, S. Voruganti, H. Wang, W.-D. Zhang ...
  • Qin. J.-J., W. Wang, S. Voruganti, H. Wang, W.-D. Zhang ...
  • Qin. J.-J., W. Wang and R. Zhang (۲۰۱۷). Experimental therapy ...
  • Raza. S., J. E. Ohm, A. Dhasarathy, J. Schommer, C. ...
  • Rong. J.-J., R. Hu, Q. Qi, H.-Y. Gu, Q. Zhao, ...
  • Saji. S., S. Nakashima, S. i. Hayashi, M. Toi, S. ...
  • Salahshoor. M. R., M. M. Mohammadi, S. Roshankhah and C. ...
  • Shafaghat. A. (۲۰۱۰). Free radical scavenging and antibacterial activities, and ...
  • Shangary. S., D. Qin, D. McEachern, M. Liu, R. S. ...
  • Shangary. S. and S. Wang (۲۰۰۹). Small-molecule inhibitors of the ...
  • Sjöström. J., C. Blomqvist, P. Heikkilä, K. Von Boguslawski, A. ...
  • Soudamani. S., S. Yuvaraj, T. Malini and K. Balasubramanian (۲۰۰۵). ...
  • Subash-Babu. P., G. M. Alshammari, S. Ignacimuthu and A. A. ...
  • Syed Najmuddin. S. U., M. F. Romli, M. Hamid, N. ...
  • Talib. W. H., S. A. Al-Hadid, M. B. W. Ali, ...
  • Tovar. C., J. Rosinski, Z. Filipovic, B. Higgins, K. Kolinsky, ...
  • Vassilev. L. T., B. T. Vu, B. Graves, D. Carvajal, ...
  • Vu. B., P. Wovkulich, G. Pizzolato, A. Lovey, Q. Ding, ...
  • Wang. C. H., J. M. Yang, Y. B. Guo, J. ...
  • Wang. H., X. Ma, S. Ren, J. K. Buolamwini and ...
  • Wang. H. and C. Yan (۲۰۱۱). A small-molecule p۵۳ activator ...
  • Wang. W., E. R. Rayburn, J. Hang, Y. Zhao, H. ...
  • Wang. W., E. R. Rayburn, Y. Zhao, H. Wang and ...
  • Wang. W., H. Wang, E. Rayburn, Y. Zhao, D. Hill ...
  • Wiley. C. D., N. Schaum, F. Alimirah, J. A. Lopez-Dominguez, ...
  • Xiong. J., J. Li, Q. Yang, J. Wang, T. Su ...
  • Xiong. J., T. Su, Z. Qu, Q. Yang, Y. Wang, ...
  • Xu. Y. (۲۰۰۸). Induction of genetic instability by gain-of-function p۵۳ ...
  • Zawacka‐Pankau. J. and G. Selivanova (۲۰۱۵). Pharmacological reactivation of p۵۳ ...
  • Zhou. R., H. Chen, J. Chen, X. Chen, Y. Wen ...
  • نمایش کامل مراجع