A Novel Sintered Porous Micromixer for the Effective Mixing of Biologics and Scale Model Investigation of Micromixing Mechanisms

Publish Year: 1392
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_JAFM-5-4_010

تاریخ نمایه سازی: 5 بهمن 1400

Abstract:

This paper presents a parametric investigation of a porous ۳D micro-mixer as well as a ۱۰:۱ scale model of the same used to examine the influence of the contributions of both diffusion and advection to successful mixing of fluids of different viscosity. Experiments at both scales implement the laser induced fluorescence technique to capture the evolution of concentration gradients at the mixer outlet. Mixing performance strongly increases with flow rate in the micromixing apparatus but only moderately in the scale-up suggesting important scale-dependent manipulation of diffusion.

Authors

J. Stevens

Bio Surgery Exploratory Group, Baxter R&D Europe, Alliance Park, Braine-l’Alleud, Belgium

G. Brossard

Bio Surgery Exploratory Group, Baxter R&D Europe, Alliance Park, Braine-l’Alleud, Belgium

A. Blom

Bio Surgery Exploratory Group, Baxter R&D Europe, Alliance Park, Braine-l’Alleud, Belgium

A. Douteur

Bio Surgery Exploratory Group, Baxter R&D Europe, Alliance Park, Braine-l’Alleud, Belgium

Y. Delmotte

Bio Surgery Exploratory Group, Baxter R&D Europe, Alliance Park, Braine-l’Alleud, Belgium