Honey with Coffee: A new finding in the treatment of Persistent Postinfectious Cough

Publish Year: 1389
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_IJOTO-23-2_001

تاریخ نمایه سازی: 11 بهمن 1400

Abstract:

Introduction: Persistent postinfectious cough (PPC) is a cough that persists longer than ۳ weeks or perhaps for many months after a common cold or an upper respiratory tract infection (URTI). PPC has poor response to routine treatment modalities, so it can be a vexing problem for the patient and the physician alike. Our hypothesis was that honey and/or coffee have some beneficial effects in the treatment of PPC. The aim of this study was to evaluate the therapeutic effects of coffee and/or honey in the treatment of patients with PPC. Materials and Methods: This was a double blind randomized clinical trial, conducted on adult patients during a ۶-year period from ۲۰۰۳ to ۲۰۰۹. Included in this study were ۸۴ adult participants that had experienced PPC longer than ۳ weeks. All of them had the history of several referrals to different physicians and despite treatment, their cough had persisted. Patients with other causes of chronic cough, or systemic disease or with abnormal routine laboratory tests were excluded. All the included ۸۴ participants were distributed into three groups. For all the participants, a jam-like paste was prepared. Each ۶۰۰ grams of the product consisted of "۷۰ grams original instant coffee" in the first regimen, "۵۰۰ grams of honey" in the second regimen and "۷۰ grams of instant coffee plus ۵۰۰ grams of honey" in the third regimen. These participants were told to dissolve ۲۵ grams of the prescribed product in about ۲۰۰ CC of warm water (under ۶۰o C), and drink this solution every ۸ hours for one week. All the participants were evaluated before and at the end of the first week of their treatment, to measure the frequency of their cough. In addition they were under observation for the first month. Results: Comparing the effectiveness of all three treatment regimens, this study found "honey with coffee" as the most effective treatment modality for PPC (P<۰.۰۰۱). Conclusions: Combination of honey and coffee can successfully treat the PPC at a short time. Thus, it is recommended for the treatment of PPC.

Keywords:

Coffee , Honey , Postinfectious cough , Upper respiratory tract infection

Authors

Mohammad-Ali Raeessi

Department of otorhinolaryngology, Baqiyatallah University of Medical Sciences. Tehran, Iran

Jafar Aslani

Department of pulmonology, Baqiyatallah University of Medical Sciences. Tehran, Iran

Homa Gharaie

Natural Medicines Office in Deputy of Food and Drug, Ministry of Health and Medical Educations,Tehran, Iran

Ali-Akbar Karimi Zarchi

Department of epidemiology and biostatics, Faculty of Health, Baqiyatallah University of Medical Sciences, Tehran, Iran

Neda Raeessi

Research Center of Tehran University of Medical Sciences, Tehran, Iran

Shervin Assari

Deputy of Research, Baqiyatallah University of Medical Sciences. Tehran, Iran