Impact of Quercetin on Sperm Parameters, Testicular Tissue and Sex Hormone: a Systematic Review
Publish place: Jorjani Biomedicine Journal، Vol: 9، Issue: 4
Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JOBJ-9-4_004
تاریخ نمایه سازی: 24 بهمن 1400
Abstract:
Background and Objective: Quercetin is a polyphenolic flavonoid compound with a potent antioxidant impact, proposed to make a drastic contribution in treating male infertility. The current systematic review aimed to provide an overview of previous studies about quercetin's impact on male infertility.
Material and Methods: Electronic search with MeSH words including Quercetin, Infertility, Sperm, Testicular tissue, and Sex hormones was accomplished in databases Web of Science, Scopus, Science Direct, Wiley, NCBI, and Google Scholar. Finally, ۲۹۶ articles were recognized during the primary search. A total of ۱۴۴ papers,passing the analysis stage containing Identification, Screening, and Eligibility were selected for assessment.
Results: Quercetin prevents damage to the testicular germinal epithelium and facilitates the spermatogenesis process by strengthening the antioxidant system, reducing lipid peroxidation and oxidative stress, preventing the expression of pro-apoptotic genes, increasing testosterone and gonadotropins.
Conclusion: In conclusion, the present review showed that quercetin by its antioxidant impacts, can counteract various toxins that induce oxidative stress in the male reproductive system.
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Authors
Fahimeh Hosseinabadi
Academic Center for Education, Culture and Research, Arak, Iran
Tayebeh Faraji
Academic Center for Education, Culture and Research, Arak, Iran
Mahdi Malmir
Department of Midwifery, Tuyserkan Branch, Islamic Azad University, Tuyserkan, Iran
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