Bleeding Management In Rhinoplasty Surgery: A Systematic Review Study On Clinical Trial Studies Conducted In Iran

Introduction: Bleeding during rhinoplasty surgery is a complication that reduces the surgeon's vision and quality of surgery and causes multiple problems for the surgeon and anesthesiologist. So far, various methods have been performed to reduce bleeding during rhinoplasty. Therefore, this study aimed to evaluate the effectiveness of medications on the rate of bleeding during rhinoplasty surgery as a systematic review of clinical trial studies conducted in Iran. Methods: In this systematic review study, SID, Magiran, Scopus, Science Direct, Medline, and PubMed databases and Google Scholar search engine were quarried from ۲۰۰۰ to ۲۰۲۰ using Persian and English keywords. The quality of the included articles was evaluated using a checklist related to clinical trial studies. Results: Fourteen studies were included in this study. Among the studies, ۴ studies were related to tranexamic acid, ۳ studies on clonidine and Dexmedetomidine, ۲ studies on nitroglycerin and labetalol, and one study on remifentanil, magnesium sulfate, dexamethasone, epinephrine, and lidocaine. In all studies performed in Iran, all medications except epinephrine reduced the amount of bleeding during rhinoplasty surgery. However, some studies did not show a significant difference in reducing bleeding between the compared medications. Conclusion: It seems that tranexamic acid can be more effective in reducing or controlling bleeding during rhinoplasty surgery than other medications.

Keywords:

Bleeding , Rhinoplasty , Iran , Clinical trial.