Selecting anti-seizure medication in new-onset epilepsy

In approaching to a patient with a new-onset seizure, first, it should determine whether it is a true epileptic seizure or a non-epileptic event. The next step is determining whether the seizure is provoked or unprovoked. If the seizure is unprovoked, does it fulfill the criteria of epilepsy and warrants long-term antiseizure medication (ASM). In selecting ASM, the patient’s epilepsy type and co-morbid condition is a main concern. All the above issues will be discussed in detail