Epigallocatechin Gallate, a Unique Natural Compound with Tremendous Health Benefits

Epigallocatechin Gallate, a Unique Natural Compound with Tremendous Health Benefits         Wenli Sun۱, Mohamad Hesam Shahrajabian۱, and Qi Cheng۱,۲*     ۱Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing ۱۰۰۰۸۱, China ۲College of Life Sciences, Hebei Agricultural University, Baoding, Hebei, ۰۷۱۰۰۰, China; Global Alliance of HeBAU-CLS&HeQiS for BioAl-Manufacturing, Baoding, Hebei ۰۷۱۰۰۰, China.   *Corresponding author E-mail: [e-mail]; [e-mail];       Received: ۱۰ Agust ۲۰۱۸                                              Accepted: ۱۰ January ۲۰۱۹                                     Abstract Epigallocatechin gallate is a tea catechin. It is predominatly found in tea (green, white, oolong and black teas), fruits (cranberries, strawberries, blackberries, kiwis, cherries, pears, peaches, apples and avocados), and nuts (pecans, pistachios, and hazelnuts). Catechins may be further categorized into a larger group of plant compounds known as polyphenols. Epicatechin, epigallocateching and epicatechin ۳-gallate also offer similar benefits.  The most important pharmacological activities of EGCG are antineoplastic, HIV infection, hypertension and associated complications, type II diabetes mellitus, its usage as cardioprotective, hepatoprotective, nephroprotective, and its application in Alzheimer, Parkinson, and Osteoporosis. Its importance in cancer treatment is because of natural origin, safety, and low cost, but the main problem is its low bioavailability with various major limitations in EGCG studies.   Key words: Natural Compounds, Caner, Tea, Epigallocatechin.  

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Key words: Natural Compounds , Caner , tea , Epigallocatechin