The Most Important Pharmaceutical Benefits of Sulforaphane, a Sulfur-Rich Compound in Cruciferous

Publish Year: 1398
نوع سند: مقاله ژورنالی
زبان: English
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JR_ROCE-14-2_001

تاریخ نمایه سازی: 24 اسفند 1400

Abstract:

The Most Important Pharmaceutical Benefits of Sulforaphane, a Sulfur-Rich Compound in Cruciferous     Mohamad Hesam Shahrajabian۱,۲, Wenli Sun۱, and Qi Cheng۱,۲* ۱-Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing ۱۰۰۰۸۱, China ۲-College of Life Sciences, Hebei Agricultural University, Baoding, Hebei, ۰۷۱۰۰۰, China; Global Alliance of HeBAU-CLS&HeQiS for BioAl-Manufacturing, Baoding, Hebei ۰۷۱۰۰۰, China.   *Corresponding author E-mail: chengqi@caas.cn; hesamshahrajabian@gmail.com   Received: ۱۰ March ۲۰۱۹                                             Accepted: ۲۰ June ۲۰۱۹     Abstract Natural products have played a key role in drug discovery and development in modern days. Sulforaphane can be found in a wide variety of cruciferous vegetables, including cabbage, Brussels sprouts, cauliflower, broccoli, Chinese broccoli, broccoli sprouts, broccoli raab, Kohlrabi, collards, kohlrabi, mustard, turnip, kale and radish. The most important health benefits of sulforaphane is its effects again breast cancer, lung cancer cells, human liver cancer cells, gastric cancer cell lines, ovarian cancer, prostate cancer, pancreatic cancer, colon cells cancer, treatment of cancer cell senescence, anti-inflammatory properties, antineoplastic agent, reduction of placental and endothelial oxidative stress, potential in mixed granulocyte asthma, treatment of various neurological disorders, protection again skeletal muscle disease, anti-allergic and its impact against oxidative stress.   Keywords: Natural Compounds, Sulforaphane, Health Benefits, Cancer.    

Authors

WENLI SUN

-Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing ۱۰۰۰۸۱, China

Mohamad Hesam Shahrajabian

Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing ۱۰۰۰۸۱, ChinaSenior Researcher- Faculty of Agriculture- Islamic Azad University, Isfahan (Khorasgan) Branch, Isfahan, Iran

HONG SHEN

College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, Zhejiang, China

MEHDI KHOSHKHARAM

Faculty of Agriculture, Islamic Azad University, Isfahan (Khorasgan) Branch, Isfahan, Iran

QI CHENG

۱-Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing ۱۰۰۰۸۱, China ۴-College of Life Sciences, Hebei Agricultural University, Baoding, Hebei, ۰۷۱۰۰۰, China; Global Alliance of HeBAU-CLS&HeQiS for BioAl-Manufacturi