Publisher of Iranian Journals and Conference Proceedings

Please waite ..
Publisher of Iranian Journals and Conference Proceedings
Login |Register |Help |عضویت کتابخانه ها
Paper
Title

Design of a diagnostic kit for anti-TSH antibody to newborn hypothyroidism

Year: 1400
COI: HWCONF08_054
Language: EnglishView: 70
This Paper With 5 Page And PDF Format Ready To Download

Buy and Download

با استفاده از پرداخت اینترنتی بسیار سریع و ساده می توانید اصل این Paper را که دارای 5 صفحه است به صورت فایل PDF در اختیار داشته باشید.
آدرس ایمیل خود را در کادر زیر وارد نمایید:

Authors

Neda Shakarian - Department of Clinical Biochemistry, Faculty of Medical Sciences, Dezful University of Medical Sciences, Dezful, Iran,
Maysam Mard Soltani - Department of Clinical Biochemistry, Faculty of Medical Sciences, Dezful University of Medical Sciences, Dezful, Iran,
Sima Nasri - Department of Biology, Payame Noor University, Tehran, Iran,
Mohammad Javad Rasaee - Department of Medical Biotechnology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran,
Saeed Khalili - Department of Biology Sciences, Shahid Rajaee Teacher Training University, Tehran, Iran,

Abstract:

Neonatal hypothyroidism can cause lifelong mental and physical disorders in humans. Failure to diagnose early can lead to irreparable harm to infants. It can be easily managed with timely detection. Screening programs to diagnose hypothyroidism rely on safety methods in most countries. This method is time consuming, requires laboratory equipment and must be performed by a skilled technician. Therefore, ELISA is not the preferred method for diagnosing neonatal hypothyroidism and can be used as a confirmatory method in infants suspected of having neonatal hypothyroidism. To design a kit, we must first obtain gold-conjugated antibodies. For the synthesis of nanoparticles, a concentration of ۱% in ۱ ml of water was added to ۰.۸ mg of gold nanoparticle powder (HAuCL۴) and heated for ۳ minutes to turn pink. A size analyzer was used to determine the effective diameter of the synthesized gold nanoparticles. Experimentation and pairing with antibodies and evaluation of color and color intensity were evaluated in this study and particle size of ۵۰ nm was considered. Then, using SR۹۵-۱, SR۹۵-۲, and SR۹۵-۳ polyclonal antibodies, which were designed in the previous study against human TSH, along with monoclonal antibodies were used in the kit design. The results of this study showed that these conjugated antibodies can be used to diagnose neonatal hypothyroidism.

Keywords:

Paper COI Code

This Paper COI Code is HWCONF08_054. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1439311/

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Shakarian, Neda and Mard Soltani, Maysam and Nasri, Sima and Rasaee, Mohammad Javad and Khalili, Saeed,1400,Design of a diagnostic kit for anti-TSH antibody to newborn hypothyroidism,8th International Conference on Health, Treatment and Health Promotion,https://civilica.com/doc/1439311

Research Info Management

Certificate | Report | من نویسنده این مقاله هستم

اطلاعات استنادی این Paper را به نرم افزارهای مدیریت اطلاعات علمی و استنادی ارسال نمایید و در تحقیقات خود از آن استفاده نمایید.

Scientometrics

The specifications of the publisher center of this Paper are as follows:
Type of center: علوم پزشکی
Paper count: 305
In the scientometrics section of CIVILICA, you can see the scientific ranking of the Iranian academic and research centers based on the statistics of indexed articles.

Share this page

More information about COI

COI stands for "CIVILICA Object Identifier". COI is the unique code assigned to articles of Iranian conferences and journals when indexing on the CIVILICA citation database.

The COI is the national code of documents indexed in CIVILICA and is a unique and permanent code. it can always be cited and tracked and assumed as registration confirmation ID.

Support