Comparison of Serum level of Vitamin D in Pregnant Women with Preeclampsia and a Control Group in Ayatollah Mousavi Hospital in Zanjan
Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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JR_JOGCR-7-4_010
تاریخ نمایه سازی: 31 خرداد 1401
Abstract:
Background & Objective: Conflicting results have been reported about the association between vitamin D and preeclampsia. The aim of the current study is to compare the serum levels of vitamin D in preeclamptic, and non-preeclamptic pregnant women admitted to the Ayatollah Mousavi Hospital in Zanjan.
Materials & Methods: In this case-control study, ۱۲۰ pregnant women were selected using convenience sampling in Zanjan in ۲۰۱۸-۲۰۱۹. Then they were divided into two groups, preeclampsia and non- preeclampsia. Both groups were matched one by one. The data were collected using a demographic information questionnaire and a researcher-made checklist. After obtaining consent from participants, blood samples were collected using the peripheral venous catheter. Then the ELISA test was used to measure vitamin D in participants. Data were analyzed by SPSS version ۱۶ using, independent t-test, and Chi-square test (P≤۰.۰۵).
Results: Of the participants, ۶۴ (۵۳.۴ %) were between ۲۰-۳۵ years old, ۴۸ (۴۰%) were older than ۳۵ years, and ۸ (۶%) were younger than ۲۰ years. Most of the participants' gestational age was between ۳۴ and ۳۹ weeks (۸۹.۱%). The Mean (SD) of serum level of vitamin D was significantly higher in healthy pregnant women (۱۹.۰۶ (۷.۴۸)) than women with preeclampsia (۱۶.۶۰ (۵.۸۷)) (P<۰.۰۱). Among those with preeclampsia, the highest vitamin D level (۱۷.۱۷) was observed at ۳۷-۳۹ weeks of gestation. The lowest level (۱۰.۸) was for those with less than ۳۴ weeks gestational age.
Conclusion: This study demonstrated that vitamin D could be a protective factor for preeclampsia in pregnant women. However, further studies are recommended.
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Authors
Hamideh Gholami
Department of Perinatology, School of Medicine, Zanjan University of Medical Science, Zanjan, Iran
Sanaz Fayazi
Faculty of Nursing and Midwifery, Zanjan University of Medical Sciences, Zanjan, Iran
Maryam Shirshekan
Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Nima Motamed
Zanjan University of Medical Science, Zanjan, Iran
Shabnam Tofighi
Department of Perinatology, School of Medicine, Zanjan University of Medical Science, Zanjan, Iran
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