Dose Nitroglycerine enhance detection of viable myocardium by Tl-۲۰۱ SPECT? [Persian]

Publish Year: 1381
نوع سند: مقاله ژورنالی
زبان: English
View: 18

نسخه کامل این Paper ارائه نشده است و در دسترس نمی باشد

  • Certificate
  • من نویسنده این مقاله هستم

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_IRJNM-10-1_009

تاریخ نمایه سازی: 7 تیر 1401

Abstract:

It is suggested that sublingual nitroglycerine can improve the ability of T۱-۲۰۱ for detection of viable myocardium. Methods and Results: In a randomized, double blind study, ۵۰ patients who had fixed defects on stress-redistribution scan, were randomized into two groups. In group I, patients received ۰.۴-۰.۸ mg sublingual nitroglycerine, before T۱-۲۰۱ reinjection. In group II, reinjection of T۱-۲۰۱ was performed, without any previous intervention. In group I, ۱۱ (۴۴%) of the patients showed improved reversibility after T۱-۲۰۱ reinjection compared with ۹ (۳۶%) of group II patients (P=۰.۵۶). Moreover, ۶ of all patients showed reverse redistribution. This pattern was observed in ۴ (۱۶%) of the patients in group I and ۲ (۸%) of group II patients (P=۰.۳۸). Conclusion: Nitroglycerine has no significant effect on detection of reversible myocardium by T۱-۲۰۱ SPECT. Occasionally, T۱-۲۰۱ reinjection causes reverse redistribution, but nitroglycerine has no effect on it.

Authors

Mohammad Eftekhari

Research Institute for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran

Maryam Shahidzadeh Mahani

Research Institute for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran

Armaghan Fard-Esfahani

Research Institute for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran

Abbas Takavar

Research Institute for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran

Mohsen Saghari

Research Institute for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran