Evaluation of response to I-۱۳۱ ablative therapy in patients with differentiated thyroid carcinoma: A five year retrospective study [Persian]

Differentiated thyroid carcinomas usually show good uptake and response to I-۱۳۱ ablative treatment. In this study, ۹۰ patients following near total thyroidectomy who were referred to our institute for I-۱۳۱ therapy are retrospectively studied. The patients are divided in two groups. Group ۱ revealed complete ablation after one dose of I-۱۳۱. Group ۲ needed more than one dose of I-۱۳۱ for ablation. ۲۶ patients (۲۸.۹%) were Categorized in group ۱ and ۶۴ patients (۷۱.۱%) in group ۲ patients. Comparison between the two groups revealed the highest success rate (Ablation with one dose of I-۱۳۱) in male patients between ۳۰-۵۰ years of age, with mixed type of differentiated thyroid carcinoma without any evidence of local or distant metastasis.