Synthesis, characterization, theoretical calculations and biological studies of nano Sodium tetrafluoroborate (III)
Publish place: International Journal of Nano Dimension، Vol: 3، Issue: 1
Publish Year: 1391
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJND-3-1_003
تاریخ نمایه سازی: 24 تیر 1401
Abstract:
Synthesis, characterization, spectral and theoretical calculations of sodium tetrafluoroborate (III) (STFB) has been studied in this research. Sodium tetrafluoroborate (III) was synthesized by a sonochemical method and characterized by IR, UV/VIS, ۱۱B-NMR and Mass spectrometer techniques. The nano compound was characterized by scanning electron microscopy (SEM), X-ray powder diffraction (XRD) and IR spectroscopy. The structure of synthesized compound was optimized at the B۳LYP/LANL۲DZ level of theory and theoretical parameters such as structural data, molecular specifications, and infrared spectra were extracted by using Gaussian ۰۳ program. Theoretical data show good agreement with the experimental results. Biological properties of this compound such as antitumor and antibacterial properties studied. This new complex showed excellent antitumor activity against one kind of cancer cells that is K۷۴۲ (human chronic myeloid leukemia) cells. Also the compound was tested against the bacterial species Staphylococcus aureus, Escherichia coli, Staphylococcus Epidermidis, Estreptococo B and Shigella.
Keywords:
Sodium tetrafluoroborate (III) , Nano-particle preparation , Optimized , Antitumor activity , K۷۴۲ (human chronic myeloid leukemia) cells , Antimicrobial Activity
Authors
Sh. Ghammamy
Department of Chemistry, Faculty of Science, Imam Khomeini International University, Qazvin, Iran.
Sh. Keysan
Department of Chemistry, Islamic Azad University, Ardabil Branch, Ardabil, Iran.