Molybdenum Disulfide/Graphene Oxide Nanohybrid as an Electrocatalyst for Sensitive Detection of Carbamazepine in Human Body Fluid Samples

Molybdenum disulfide as a transition metal dichalcogenide was prepared by a hydrothermal method and hybridized with graphene oxide (MoS۲/GO). The as-prepared materials were investigated by Fourier transform infra-red spectroscopy (FT-IR), X-ray diffraction (XRD), energy dispersive X-ray elemental analysis (EDX) techniques as well transmission electron microscopy (TEM) image. The nanomaterial with its electrocatalytic properties was applied as an electro-nanocatalyst for loading on a glassy carbon electrode (MoS۲/GO-GCE) for detection of carbamazepine as an anti-epileptic in real body samples. The simple and low-cost developed electrochemical sensor detected carbamazepine with a vast linear concentration range(۳۰-۳۵۰nM), very low detection limit about ۶.۰nM and significant sensitivity equal to ۰.۱۳۴µA/nM.

Keywords:

Carbamazepine , Transition metal dichalcogenides , Electrocatalyst , Sensor