Cu/PDA/CCE as A Sensitive Electrode for Concurrent Determination of Ascorbic Acid and Folic Acid

Publish Year: 1399
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_IJAC-7-2_010

تاریخ نمایه سازی: 1 مرداد 1401

Abstract:

Herein, the electrooxidation of ascorbic acid and folic acid, as two essential vitamins, on the surface of the carbon ceramic electrode modified by polydopamine and copper (Cu/PDA/CCE) was investigated. Poly dopamine was fabricated by applying electro deposition conditions. Initial electrochemical characteristics were performed to study the behavior of the fabricated electrode for simultaneous detection of two biomolecules. From voltametric studies using the developed electrode, two separated anodic peaks for folic acid and ascorbic acid were found promisingly for concurrent detection of the compounds. Linear calibration diagrams were obtained in the range of ۰.۵ to ۳۶۰ μM and ۰.۸۳ to ۳۸۰ μM with detection limits of about ۰.۰۳۱ and ۰.۰۵۷ μM for folic acid and ascorbic acid, respectively. The developed electrode was applied in human urine sample analysis with satisfying results

Authors

Tahereh Rohani

Department of Chemistry, Payame Noor University, PO Box ۱۹۳۹۵-۴۶۹۷, Tehran, Iran

Sayed Zia Mohammadi

Department of Chemistry, Payame Noor University, PO Box ۱۹۳۹۵-۴۶۹۷, Tehran, Iran

Amirkhosro Beheshti

Department of Chemistry, Payame Noor University, PO Box ۱۹۳۹۵-۴۶۹۷, Tehran, Iran

Hooshang Hamidian

Department of Chemistry, Payame Noor University, PO Box ۱۹۳۹۵-۴۶۹۷, Tehran, Iran

Nasrin Gholamhosein Zadeh

Department of Chemistry, Payame Noor University, PO Box ۱۹۳۹۵-۴۶۹۷, Tehran, Iran

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