Effect of High-Intensity Interval Training with Eryngium Campestre on Lipid Profile and Glycemic Indices in High-Fat Diet-Induced Obese Rats

Background: Obesity is a multi-factorial physical disorder that results in high serum lipid levels and glycemic disorders. On theother hand, regular exercise and administration of Eryngium Campestre (EC) have glucose and lipid-lowering effects.Objectives: The present study aimed to review the effect of high-intensity interval training (HIIT) with EC on lipid profile andglycemic indices in high-fat diet (HFD)-induced obese rats.Methods: Twenty-four obese rats were divided into four groups, including: (۱) control, (۲) HIIT, (۳) EC, and (۴) HIIT+EC. To investigatethe effect of obesityonresearch variables, six rats were assigned to a healthy control group. During six weeks, groups ۲and۴receivedHIIT three days per week, and groups ۳ and ۴ received ۳۰ mg/kg EC by gavage. Data were analyzed using the Shapiro-Wilk test andone-way ANOVA with Tukey’s post hoc test (P ۰.۰۵).Results: Obesity significantly increased cholesterol (Cho), triglyceride (TG), insulin, and glucose levels (P ۰.۰۵). However, HIITsignificantly decreased Cho, TG, insulin, and glucose levels (P ۰.۰۵), and EC significantly decreased Cho, TG, low-density lipoprotein(LDL), insulin, and glucose levels (P ۰.۰۵). Besides, HIIT+EC significantly decreased LDL and insulin (P ۰.۰۵). HIIT+EC coulddecrease LDL more than did HIIT (P ۰.۰۵).Conclusions: Although HIIT and EC alone improved the lipid profile and glycemic indices in obese rats, HIIT combined with EC hadgreater effects on the decrease of LDL compared to HIIT.

Keywords:

High-Intensity Interval Training , Eryngium , Lipids , Glycemic Index