Association of serum adiponectin levels with pulmonary artery pressure in maintenance hemodialysis patients
Publish place: Journal of Renal Endocrinology، Vol: 3، Issue: 1
Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JRE-3-1_005
تاریخ نمایه سازی: 30 مرداد 1401
Abstract:
Introduction: Abnormal pulmonary artery pressure (PAP) in hemodialysis patients is associated with significant increase in morbidity and mortality.Objectives: Considering the significance of pulmonary hypertension in hemodialysis patients, a study was designed to assess the association of serum adiponectin levels and PAP in a group of stable hemodialysis patients.Patients and Methods: The study was conducted on a group of non-diabetic hemodialysis patients. The study was carried out in hemodialysis ward of Shahrekord University of Medical Sciences for a period of ۴ months in ۲۰۱۳. The studied patients had a history of dialysis from ۱ to ۲۲ years.Results: In our study, out of ۷۶ hemodialysis patients, ۴۶.۱% were female and ۵۳.۹% were male. The mean PAP in female hemodialysis patients was ۲۹.۷۴ mm Hg, which was about ۹% less than the PAP observed in male hemodialysis patients. Mean adiponectin levels in all the patients, males, and females, respectively, was ۱۰.۵۹, ۱۰.۴۲, and ۱۰.۸۰ μg/mL respectively. In this study a significant and positive relationship between adiponectin levels and PAP in female hemodialysis patients (r = ۰.۳۵, P = ۰.۰۴) was detected.Conclusion: This association requires more investigation on the significant role of adiponectin in hemodialysis patients.
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Authors
Mohammad Reza Tamadon
Department of Internal Medicine, Semnan University of Medical Sciences, Semnan, Iran
Maryam Heidari
Department of Internal Medicine, Division of Nephrology, Shahrekord University of Medical Sciences, Shahrekord, Iran
Saeed Mardani
Department of Internal Medicine, Division of Nephrology, Shahrekord University of Medical Sciences, Shahrekord, Iran