Surface modification of Polyurethane as a Novel Skin Dress
Publish place: 1st New and Advanced Materials International Congress
Publish Year: 1391
نوع سند: مقاله کنفرانسی
زبان: English
View: 1,845
This Paper With 5 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
NAMIC01_051
تاریخ نمایه سازی: 18 تیر 1391
Abstract:
The aim of this study is to design and fabricate an artificial skin dress for the purpose of skin healing. A multilayer skin dressing included castor oil-based polyurethane synthesized as the outer layer and two biopolymeric layers of heparin and chitosan as the inner layers were fabricated. The surface of polyurethane was activated using two steps oxygen radio frequency (RF) plasma. The surface of the modified PU films characterized by attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy, and water drop contact angle measurements. The ATR-FTIR spectrogram of the modified films showed new characteristic peaks of PU. Also, heparin and chitosan were successfully immobilized on PU films. In vitro cell culture study on the chitosan/heparin immobilized PU and poly (acrylic acid)-grafted PU films showed compatibility of modified surfaces as well as virgin film with L929 fibroblast cells. Cell adhesion and proliferation of cells on the chitosan/heparin immobilized surfaces showed better behavior compared with poly (acrylic acid)-grafted PU. It was concluded that chitosan/heparin-immobilized surfaces can have a good potential to be used as a skin replacement
Keywords:
Authors
S. A. Ayati Najafabadi
Biomaterials Group, Biomedical Engineering Faculty, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :