Some Metal Ions Complexes With Azo [۴-((۸-hydroxyquinolin-۷-yl)-N(۴-methylisoxazol-۳-yl)benzenesulfonamide] Synthesis, Characterization, Thermal Study and Antioxidant Activity

A new azo (LH) ligand was prepared by coupling reaction between, diazonium salt of Sulfamethoxazole, and ۸-hydroxyquinoline in a process called diazotization process resulting in azo-ligand [۴-((۸-hydroxyquinolin-۷-yl)-N(۴-methylisoxazol-۳-yl) benzene sulfonamide]. The azo ligand was identified by using spectroscopic techniques to detect and characterize the formation of ligand and complexes of Ni۲+, Pt۴+, Pd۲+, and Rh۳+ metal ions, and to determine the chelating behavior of ligand and also its bind position. All complexes have a [۱:۱] [M-ligand] ratio and all complexes are non-electrolytes and most of the complexes have octahedral geometry, while Pd۲+complex gave square planer geometry and Ni ۲+ complex indicate tetrahedral geometry. Thermal decomposition TGA and DSC results reveal the presence of coordinated water molecules in the complexes. Antioxidant activities of these compounds were evaluated against (DPPH) radical and were compared with the standard natural antioxidant, ascorbic acid. The findings show that these compounds exhibit excellent radical scavenging activities. The geometries were detected depending on Ultra Violet-visible (UV-Vis) technique and according to the Fourier Transform Infrared Spectroscopy (FT-IR) and Liquid Chromatography-mass (LC-Mass) studies; we can also detect the chelating behavior of ligand. While the conductivity properties can be detected by conductivity measurements. In addition, element micro analysis and atomic absorption gave compatible results with theoretically calculated results, and many other techniques support the formation of ligand and occurrence of coordination including (Proton and Carbon - nuclear magnetic resonance (۱H & ۱۳C-NMR) and magnetic quantifications.

Keywords:

Sulfamethoxazole , mass spectroscopy , Antioxidant , Azo dye , Thermal analysis