Structural, Characterization, and Biological Activity of Novel Schiff Base Ligand Derived from Pyridoxal with ۲-Aminobenzothazol and Its Complexes

A [VO(II), Mn(III), Fe(II), Co(II), Ni(II), Cu(II), and Pt(IV)] complexes prepared from ۴-((benzo [d] thiazol-۲-yl imino) methyl)-۵- (hydroxymethyl)-۲-methylpyridin ۳-ol, ligand (HL۱) Schiff bases is newly synthesized which is derived from the reaction between one equivalent of (pyridoxal hydrochloride) and one equivalent for (۲-aminobenzothiazole). Multiple techniques and devices were used to diagnose the prepared compounds. Among these techniques are Melting Point Measurements, Fourier Transform Infrared Spectra, Conductivity Measurements, Electronic spectra UV-Vis., Mass Spectroscopy, Metal Analysis, Elemental Microanalysis, Magnetic Moment Measurement, Thermal Gravimetric Analysis TGA, ۱H, and ۱۳C-NMR Spectra. Then, it was measured the biological activity of the prepared compounds against four types of bacteria (Klebsiella pneumoniae and pseudomonas) (G-), (Staphylococcus aureus and bacillus subtilis) (G+), and a one type of fungus (Candida albicans).

Keywords:

Pyridoxal ۲ , aminobenzothazol FT , IR UV , Vis