Investigating the antibiotic resistance pattern of Escherichiacoli isolates from patients with urinary tract infection referred to ImamKhomeini Hospital in Shirvan city in ۲۰۲۱
Publish place: Twenty-third International Congress of Microbiology of Iran
Publish Year: 1401
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
MEDISM23_160
تاریخ نمایه سازی: 16 مهر 1401
Abstract:
Background and Aim : Escherichia coli is a ubiquitous causative agent in people with urinarytract infections, and antibiotic resistance is increasing worldwide. Therefore, early diagnosis andappropriate selection of antimicrobial drugs are necessary.Methods : This cross-sectional study was conducted on ۱۵۵۰ urine samples of outpatients andinpatients who referred to Imam Khomeini Hospital in Shirvan city in ۲۰۲۱. The isolates wereidentified and identified using biochemical tests and differential culture media. The antibioticresistance pattern of Escherichia coli bacteria was studied by disk diffusion or Kirby Baer method.Results : In this study, out of ۷۳ positive samples, ۴۸ (۶۵.۷%) were Escherichia coli bacteria, thehighest antibiotic resistance was related to cefazolin (۶۴%), ampicillin sulbactam (۵۰%),ceftriaxone (۴۸.۵%), respectively. ceftazidime (۴۱.۱۷%), imipenem (۴۱.۱۷%), ciprofloxacin(۳۰.۵%), gentamicin (۷.۵%) and nitrofurantoin (۲.۳%).Conclusion : In general, according to the results, the most resistant antibiotics are cefazolin andampicillin-sulbactam, which are recommended not to be prescribed due to their resistance andineffectiveness in treatment, nitrofurantoin and gentamicin are the most sensitive antibioticsrespectively.
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Authors
Moein Hamidi hesari
MSc in Microbiology, Imam Khomeini Hospital, Shirvan, North Khorasan University of Medical Sciences, Bojnourd, Iran.
Mohsen Rezaie nejad
BA in Medical Laboratory Shirvan Imam Khomeini Hospital, Shirvan, North Khorasan University of Medical Sciences, Bojnourd, Iran.
jafar hemmat
Assistant Professor of Biotechnology, Department of Biotechnology, Research Organization for Scientific and Technology, Tehran, Iran