Frequency of Cutaneous Leishmaniasis and Complete Ulcer Healing in Patients Referred to Skin Diseases and Leishmaniasis Research Center, Isfahan, Iran from ۲۰۱۸ to ۲۰۱۹

Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_JCHR-11-3_010

تاریخ نمایه سازی: 30 مهر 1401

Abstract:

Introduction: Iran is one of the most important hot spots for cutaneous leishmaniasis (CL) in the world. To date, no studies have been done on both epidemiological aspects along with the length of the treatment course of CL. This study aimed to determine the relative frequency of CL in patients with suspected skin lesions and the duration of healing after treatment with different regimens. Methods: This cross-sectional study was conducted on patients with CL referred to the skin diseases and leishmaniasis research center (SDLRC) in Isfahan during the years ۲۰۱۸ to ۲۰۱۹. Among ۳۸۹ patients with suspected skin lesions, ۱۵۰ cases were included with proven CL. Information such as age, sex, education, location, size of the lesion, duration of treatment, and the rate of recovery were recorded. SPSS software version ۲۰ was used for data analysis, the chi-square, Fisher´s Exact, and one Way ANOVA tests were used with a significant level of p < ۰.۰۵. Results: Among ۳۵۰ admitted cases, ۱۵۰ cases were CL. positive (۴۲.۸۵%). The rate of complete recovery was higher in cases with an average age of ۳۳.۵۵ ±۱۸.۹ years, but these differences were not statistically significant (P =۰.۰۷۷). There was ۳۴ cases more than the other groups in this range of age. ( The rate of complete recovery in patients with a history of migration to endemic areas was higher than in patients without a history of migration (P = ۰.۸۱)). The rate of complete recovery in patients whose means treatment duration was ۵۹.۰۳ ± ۴۱.۴۳ days was higher than other recovery periods (P = ۰.۲۳). Conclusion: The rate of complete recovery was higher in adult cases than the other groups. In this study, it was proved that the rate of recovery of patients had the significant relationship with the average duration of treatment.

Authors

لطیفه عبداللهی

Department of Biology, School of Basic Science, Science and Research Branch, Islamic Azad University, Tehran, Iran.

سید حسین حجازی

Skin Diseases and Leishmaniasis Research Center, Department of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

نور امیرمظفری

Iran University of Medical Sciences, School of Medicine, Microbiology Department, Tehran, Iran.

فتاح ستوده نژاد نعمت الهی

Department of Biology, School of Basic Science, Science and Research Branch, Islamic Azad University, Tehran, Iran.

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