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Can COVID-19 Be a Risk Factor for Tuberculosis?

Publish Year: 1400
Type: Journal paper
Language: English
View: 141

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Document National Code:

JR_SBMU-6-1_010

Index date: 31 October 2022

Can COVID-19 Be a Risk Factor for Tuberculosis? abstract

Tuberculosis is a chronic bacterial disease often caused by mycobacterium tuberculosis(1). In 2017, 10 million people were infected to and 1.6 million people died of tuberculosis (TB) (2). In patients with pulmonary TB, infectious aerosols are distributed in the air and enter other’s lungs in inspiration. It passes the mucociliary defense line and enters the pulmonary terminal alveolus where it proliferates and may get disseminated to the whole body through blood circulation. Delayed allergic reactions and cellular immunity are formed 4 to 8 weeks after infection. In 90-95% of patients, cellular immunity manages to inhibit bacillus proliferation. Though, several bacilli may persist and get reactivated in immunocompromised patients within months to years and cause re-infection and active TB (1, 3). Nearly, a third of the world’s population is carrying latent TB. Immune system suppression in patients suffering from HIV, diabetes, malnutrition, smoking, alcohol abuse, opium addiction, and immunosuppressive drugs, increases the risk of tuberculosis disease in patients with latent TB infection (3).

Can COVID-19 Be a Risk Factor for Tuberculosis? Keywords:

Can COVID-19 Be a Risk Factor for Tuberculosis? authors

Benyamin Parseh

Ph.D., Applied Cell Sciences, Faculty of Advanced Medical Technologies, Golestan University of Medical Sciences, Gorgan, Iran

Ehsan Allah Kalteh

MSc of Epidemiology, Infectious Disease Research Center, Golestan University of Medical Sciences, Gorgan, Iran

Mahnaz Sheikhi

General Practitioner, Golestan University of Medical Sciences, Gorgan, Iran

Mousa Ghelichi-Ghojogh

Ph.D. Candidate of Epidemiology, Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran