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Antiviral Vector Effects of Ivermectin on COVID-19: An Update

Publish Year: 1400
Type: Journal paper
Language: English
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Document National Code:

JR_SBMU-6-1_015

Index date: 31 October 2022

Antiviral Vector Effects of Ivermectin on COVID-19: An Update abstract

Ivermectin proposes several potentials effects, with its antimicrobial, antiviral, and anti-cancer properties. In a recently published systematic review, Ivermectin is effective on several enveloped, positive-sense, single-stranded RNA viruses such as Zika Virus, Dengue Virus, Yellow Fever Virus, West Nile Virus, Venezuelan Equine Encephalitis Virus, Chikungunya Virus, Semliki Forest Virus, Sindbis Virus, Porcine Reproductive and Respiratory Syndrome Virus, and Human Immunodeficiency Virus Type 1. Also, SARS-CoV-2 is considered as an enveloped, positive-sense, single-stranded RNA virus that was inhibited by Ivermectin in in-vitro evaluations. Although several clinical trials about the effectiveness of Ivermectin on COVID-19 are on the way, the current in vitro research is usually used in the early stages to outline new medications. Additionally, further clinical trials are required to confirm the safety and efficacy of ivermectin for human use against COVID-19 either therapeutic or preventive. We reviewed the vector effects of ivermectin on COVID-19.

Antiviral Vector Effects of Ivermectin on COVID-19: An Update Keywords:

Antiviral Vector Effects of Ivermectin on COVID-19: An Update authors

Fatemeh Heidary

International Virtual Ophthalmic Research Center (IVORC), Texas, USA

Reza Gharebaghi

International Virtual Ophthalmic Research Center (IVORC), Texas, USA

Mohammed Lateef

Department of Rehabilitation, Shahid Beheshti University of Medical Science, Tehran, Iran

Sarah Fawxi Hasan Alshmailawi

Department of Rehabilitation, Shahid Beheshti University of Medical Science, Tehran, Iran

Kahtan Alkhafaji

Department of Rehabilitation, Shahid Beheshti University of Medical Science, Tehran, Iran