Phytochemical Analysis, GCMS Identification, and Estimation of Antioxidant Activity of Iraqi Vitex negundo L.
Publish place: Journal of Medicinal and Chemical Sciences، Vol: 6، Issue: 4
Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JMCH-6-4_019
تاریخ نمایه سازی: 21 آبان 1401
Abstract:
Vitex negundo Linn, known as chaste tree, belongs to Verbenaceae family. It is a woody medicinal tree; an aromatic and flowering-ornamental plant has different ethnobotanical and pharmacological uses. The aims of this study included phytochemical analysis, detection of two flavonoids by TLC, GC/MS analysis of hexane extract, and the antioxidant estimation in leaves of Iraqi Vitex negundo activity. The results showed the important phytochemicals in hydroalcoholic and hexane extracts. In addition, the main constituents obtained by GC MS were Sabinene ۳.۲۳% and Pinene ۰.۸۷% as monoterpenes, alpha-Farnesene ۰.۵%, Pregnan-۳,۱۱-diol-۲۰-one ۱.۵۵%, and alpha-Tocopherol ۱.۵۵%. Those Iraqi Vitex negundo L. were considered as an important source for chemical constituents with a significant antioxidant activity at low concentration with IC۵۰ ۲۶.۷, as compared with ascorbic acid.
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Authors
Tahany A. Tawfeeq
Department of Pharmacognosy and Medicinal Plants, College of Pharmacy, Mustansiriyah University, Baghdad, Iraq
Amani A. Tawfeeq
Department of Pharmacognosy and Medicinal plants, Osol Al-Deen University College, Baghdad, Iraq
Rasha Eldalawy
Department of Pharmacognosy and Medicinal Plants, College of Pharmacy, Mustansiriyah University, Baghdad, Iraq
Shamis Khaleel Ibraheem
Department of Pharmacology and Toxicology, College of Pharmacy, Mustansiriyah University, Baghdad, Iraq
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