Frequency of Recurrent Transient Ischemic attack and Its Response to Anticoagulants

Background and Aim: Transient ischemic attack (TIA) most often manifests by sudden loss of motor, sensory or visual function. Recurrent TIA have been accepted as unproven indication of urgent anticoagulation therapy. The aim of this study was to evaluate the frequency of recurrent TIA and in hospital and short term prognosis    after treatment with anticoagulants. Materials and Methods: Our cross-sectional was conducted on patients with TIA in Shafa hospital in Kerman in ۲۰۱۹.  For All patients with recurrent TIA heparin (۱۰۰۰u/h) started and TCCD and CT angiography were done for all of them and the patients with significant stenosis referred for angioplasty or endarterectomy. The other patients received ۵-۷ days heparin and after that warfarin. Heparin or warfarin were disconnected whenever the patient had stroke. In hospital and short-term (three-month) prognosis were evaluated. Demographic information (age, sex) and vascular risk factors were included in a checklist, as well as patientschr('۳۹') telephone numbers for follow-up after discharge, Results: Of the ۱۲۰ patients with TIA, only ۱۵(۱۲.۵ %) had recurrent TIA. ۴ patients had significant stenosis and referred for angioplasty or endarterectomy. ۱۱ patients received anticoagulants. ۴ (۳۶.۳%) patients had stroke in hospital (۳) or in ۳ months fallow up (۱) .۷ (۶۳.۷%) were well at the end of ۳th month.  Results showed no significant relationship between response to treatment and age, sex and vascular risk factors. Conclusion: More than ۶۳% patients with recurrent TIA and no significant stenosis had good short term prognosis with anticoagulant therapy.

Keywords:

Anticoagulant , Recurrent , TIA