Evaluation of Antibacterial Activity of Iron Oxide Nanoparticles Synthesis by Extracellular Lactobacillus Against Pseudomonas Aeruginosa

This study aimed to demonstrate the biosynthetic process of iron oxide nanoparticles (Fe۲O۳-NPs) by using extracellular components produced by environmental isolates of Lactobacillus plantarum as reducing and stabilizing agents studied in the laboratory of the university of Baghdad. Add ۱ g of iron sulfate to ۱۰ mL of extracellular nanoparticles for synthesis. Biosynthetic Fe۲O۳ nanoparticles have broad application prospects in catalysis, biosensing, anticancer, and biomedicine. Optimal conditions for synthesizing Fe۲O۳ were investigated using UV-VIS, AFM, XRD, FT-IR, and FE-SEM techniques. The UV-VIS wavelength of NPs within the nanoclusters. Susceptibility testing of P. aeruginosa showed resistance to tetracycline, trimethoprim-sulfamethoxazole, ceftazidime, and chloramphenicol, whereas sensitive to Amikacin, Norfloxacin, Meropenem, and Ciprofloxacin and the effect of Fe۲O۳ NPs from extracellular component on bacteria Pseudomonas aeruginosa on an inhibition zone ۱۸ mm.

Keywords:

Fe۲O۳ NPs , Antimicrobial activity , biosynthesis nanoparticles , Pseudomonas aeruginosa , Lactobacillus plantarum , Susceptibility test , Extracellular