The Effect of Tranexamic Acid on the Blood Loss Volumes in the Patients Underwent Orthognathic Surgeries
Publish Year: 1395
نوع سند: مقاله ژورنالی
زبان: English
View: 119
This Paper With 8 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_JKMU-23-1_012
تاریخ نمایه سازی: 19 دی 1401
Abstract:
Background and Aims: Tranexamic acid has been used to decrease blood loss volumes and the subsequent need for blood transfusion in the orthopedic, spinal and cardiac surgeries. Methods: In this prospective controlled randomized clinical trial study, ۲۴ candidates for orthognathic surgeries received tranexamic acid (۲۰ mg/kg) intravenously just before the surgery while matched control patients received normal saline. The patients underwent the surgeries according to the standard protocol. Patients’ blood hemoglobin and hematocrit levels were calculated before and after the surgeries and blood loss volumes were calculated using these criteria. Results: The blood loss was estimated as ۶۹۳.۶۵ ± ۸۱.۲۴ and ۱۰۲۴.۰۰ ± ۷۵.۴۱ ml regarding blood hemoglobin values before and after the surgery in intervention and control groups, respectively; while it was estimated as ۶۶۰.۹۳ ± ۶۲.۷۸ and ۱۰۵۲.۰۰ ± ۴۸.۵۴ ml concerning patients’ blood hematocrit levels before and after the surgery in those groups, respectively. Significant differences were noted between the intervention and control patients regarding blood loss volumes determined via the two methods (both: P < ۰.۰۰۱). Conclusion: As suggested by the results, the intravenous injection of tranexamic acid (۲۰ mg/kg) just before the orthognathic surgeries was associated with the significant decreased blood loss volumes compared to the control patients.
Keywords:
Authors
Sayed Hossein Mortazavi
Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Islamic Azad University, Tehran Branch, Tehran, Iran
Hamid Hamdzadeh
Assistant Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran
Sara Afsharinia
Student of Dentistry, School of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :