Investigating the level of drug resistance of Acinetobacter baumannii strains in the intensive care units of hospitals
Publish Year: 1401
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
HWCONF11_008
تاریخ نمایه سازی: 26 دی 1401
Abstract:
Introduction: Acinetobacter are gram-negative bacteria that do not have the ability to ferment and are commonly involved in hospital infections. Acinetobacter as opportunistic hospital pathogens are resistant to a large number of antibiotics and are the cause of many infections such as bacteremia, pneumonia, meningitis, urinary tract infections and surgical wound infections.Materials and methods: During this study, ۶۰ isolates of Acinetobacter bomanii and ۴۶ isolates of other Acinetobacter species were studied. After identifying the species by using the methods of determining the sensitivity of the species to different antibiotics, it was done by using the disk diffusion method.Research findings:In this study, all isolates of Acinetobacter baumannii were resistant to the antibiotics ampicillin/sulbactam, imipenem, gentamicin, ceftazidime and ceftazidime-clavulanic acid, cefotaxime, cefotaxime/clavonic acid, amikacin, ceftriaxone, ciprofloxacin and nalidixic acid and all The isolates were sensitive to colistin and by the standard ATCC strain (PTCC ۱۸۵۵) BAA-۷۴۷ and the clinical isolates of Acinetobacter baumannii using agar disk diffusion method. Following the isolation and identification of antibiotic-resistant and beta-lactamase-producing Escherichia coli isolates by performing the golden test and phenotypic confirmation of combined discs (DDD-Test) in comparison to single discs without the presence of clavonic acid.Final conclusion: The results of this study showed that clinical isolates of Acinetobacter, especially Acinetobacter baumannii, show high resistance to antibiotics, especially third-generation cephalosporins and broad-spectrum penicillins.
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Authors
Saber Noshadi
Department of Biology, Faculty of Basic Sciences, Gachsaran Azad University
Ali Mohammadi
Department of Mathematics, Faculty of Basic Sciences, Gachsaran Azad University
Khadejeh Asadi Chahar rahe Gashin
Department of Midwifery, Faculty of Medical Sciences, Gachesaran Azad University
Lida Gholizadeh
Department of Nursing, Faculty of Medical Sciences, Gachsaran Azad University
Alireza Khodavandi
Molecular Biology Research Center, Gachsaran Azad University