La۳+-doped Co۳O۴ Nanoflowers Modified Graphite Screen Printed Electrode for Electrochemical Sensing of Vitamin B۶

In this study, we combined the advantages of good conductivity, small size, and large surface area and the catalytic property of La۳+/Co۳O۴ nanoflowers to fabricate an electrochemical sensor sensitive to determination of vitamin B۶ in real samples. La۳+/Co۳O۴ nanoflowers were synthesized by a co-precipitation method which is a convenient, environment-friendly, inexpensive process. The synthesized nanoflowers were characterized by SEM. A simple and sensitive sensor based on graphite screen printed electrode (GSPE) modified by La۳+/Co۳O۴ nanoflowers was developed for the electrochemical determination of vitamin B۶. The electrochemical behavior of vitamin B۶ was studied in ۰.۱ M phosphate buffer solution (PBS) using cyclic voltammetry (CV), chronoamperometry (CHA) and differential pulse voltammetry (DPV). The modified electrode (La۳+/Co۳O۴NFs/GSPE) showed excellent electrocatalytic activity and remarkable sensitivity towards the oxidation of vitamin B۶. The fabricated sensor displayed good operating characteristics including low detection limit, and a wide linear dynamic range for the detection of vitamin B۶. Using La۳+/Co۳O۴NFs/GSPE as the working electrode, a linear dynamic range between ۱.۰ to ۶۰۰.۰ μM and a limit of detection of ۰.۴ µM were obtained. Finally, reliability and accuracy of the proposed sensor were studied in real samples.

Keywords:

La۳+/Co۳O۴ Nanoflowers , Electrochemical sensor , Vitamin B۶ , Real samples , Modified electrode