Exosomes and Urological Cancers

Cancer is still a fatal disease compelling all communities to encounter its unfavorable burdens. Not only there is no exception for urological cancer, but also these types of cancers have an increasing trend which puts them in the top ten most common kinds of tumors. Besides, the recent COVID-۱۹ pandemic, by interrupting medical care cancer plans, caused more cancer-related problems to emerge. Although various new strategies for cancer therapy have been developed, this field still needs more improvements. Among them, cell-based treatment has great promising potential, but it has not been found completely safe. Furthermore, some evidence declares that cells’ desirable effect mainly occurs via secreting tiny vesicles which are later called exosomes. Consequently, although exosome-based remedies can probably lead to cellular treatment’s effects, this novel approach will overcome cell-related disadvantages. In addition, nowadays, enormous literature is indicating different aspects of abnormal exosome trafficking in many pathological states, confirming that more effort should be undertaken for studying and applying this mentioned structure in future cancer management and specifically, urological cancers.

Keywords:

Exosome , urological cancer , Prostate Cancer , Bladder Cancer , renal cancer