Neutrophil Gelatinase-associated Lipocalin Value in Patients' Urine with Gram Positive Cocci Infection in the Urinary Tract

Background and Aims: This study aimed to investigate the amount of Neutrophil gelatinase-associated lipocalin (NGAL) in patients' urine with Gram-positive cocci infections Materials and Methods: The microbial culture was prepared from ۱۰۰ urine samples and the results were recorded. The genus and bacterial were species identified and an antibiogram test was conducted to investigate their resistance. Human Lipocalin /NGAL enzyme-linked immunosorbent assay test was used. To analyze the data, Tukey and One Way ANOVA tests were used. Results: The highest mean of NGAL in the patient group was related to the men's category with ۸.۷۷, and the gender had a significant impact on the mean of NGAL. White blood cells has a significant impact on the mean of NGAL (p<۰.۰۵). The negative significance of the mean value also indicates the amount of NGAL being higher in the patient group. Conclusions: These data suggest a relationship between the amount of NGAL with white blood cells value in patients who present urinary infection of Gram-positive cocci. NGAL value plays an important role as an adjuvant and surrogate marker in early diagnosis of urinary tract infections and acute renal damage in line with microbiological investigations.

Keywords:

Antibiogram , Gram-positive cocci , NGAL , Urinary tract infection